Effect of dietary linoleic acid on vitamin E requirement and fatty acid composition of erythrocyte lipids in rats
| Autor: | U.M.T. Houtsmuller, F.C. Jager |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Male
food.ingredient Erythrocytes Linoleic acid medicine.medical_treatment Medicine (miscellaneous) Erythrocyte lipids Hemolysis chemistry.chemical_compound food medicine Animals Vitamin E Vitamin E Deficiency Food science Vitamin E Acetate Nutrition and Dietetics Chemistry Coconut oil Fatty Acids Thiourea Dietary Fats Lipids Rats Biochemistry Linoleic Acids Composition (visual arts) Fatty acid composition alpha-Tocopherol |
| Zdroj: | Nutrition and metabolism. 12(1) |
| ISSN: | 0029-6678 |
| Popis: | In order to investigate the effect of an increasing linoleic acid content of the diet on vitamin E requirement, young male rats were divided into 4 groups receiving respectively 0.27, 0.98, 3.57 and 12.98% linoleic acid (from mixtures of coconut oil and tocopherol-free safflower oil) in their diets. Each group was subdivided into 6 groups, receiving increasing amounts of D-α-tocopheryl acetate (2.5–23.5 mg) in their food. Spontaneous haemolysis in vitro was used as a criterion for vitamin E requirement. The amount of D-α-tocopheryl acetate needed to prevent haemolysis was 13 mg/kg food for the lowest three doses linoleic acid, the highest dose required 18 mg/kg food. The fatty acid composition of erythrocyte lipids was not influenced by the vitamin E content and only moderately by the linoleic acid content of the diet: a higher level of dietary linoleic acid caused an increase in linoleic acid content of erythrocyte lipids, which was mainly compensated by a decrease in oleic acid content. The group with the lowest dose of vitamin E and the highest dose of linoleic acid showed a significant increase in non-electrolyte (= thiourea) haemolysis time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|