Renal atrophy following gated delivery of stereotactic ablative radiotherapy to adrenal metastases
| Autor: | Famke L. Schneiders, Berend J. Slotman, Suresh Senan, A. Bruynzeel, Miguel A. Palacios, John R. van Sörnsen de Koste, Claire C van Vliet |
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| Přispěvatelé: | Radiation Oncology, CCA - Cancer Treatment and quality of life |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adrenal metastases
medicine.medical_specialty Short Communication medicine.medical_treatment R895-920 Renal function SABR volatility model Kidney Medical physics. Medical radiology. Nuclear medicine Ablative case medicine Volume reduction Radiology Nuclear Medicine and imaging Adrenal RC254-282 SABR Radiation Organ at Risk business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens Renal atrophy Radiation therapy medicine.anatomical_structure Renal dose constraints Radiology business |
| Zdroj: | van Sörnsen de Koste, J R, van Vliet, C C, Schneiders, F L, Bruynzeel, A M E, Slotman, B J, Palacios, M A & Senan, S 2021, ' Renal atrophy following gated delivery of stereotactic ablative radiotherapy to adrenal metastases ', Physics and Imaging in Radiation Oncology, vol. 20, pp. 1-4 . https://doi.org/10.1016/j.phro.2021.09.001, https://doi.org/10.1016/j.phro.2021.09.001 Physics and Imaging in Radiation Oncology, Vol 20, Iss, Pp 1-4 (2021) Physics and Imaging in Radiation Oncology, 20, 1-4. Elsevier Ireland Ltd Physics and Imaging in Radiation Oncology |
| ISSN: | 2405-6316 |
| DOI: | 10.1016/j.phro.2021.09.001 |
| Popis: | Stereotactic ablative radiotherapy (SABR) planning for adrenal metastases aims to minimize doses to the adjacent kidney. Renal dose constraints for SABR delivery are not well defined. In 20 patients who underwent MR-guided breath-hold SABR in five daily fractions of 8–10 Gy, ipsilateral renal volumes receiving ≥20 Gy best correlated with loss of renal volumes, with median renal volume reduction being 6% (range: 3%-11%, 10th-90th percentiles). Organ function did not deteriorate in 18 patients, who had post treatment renal function tests available. This suggests that the ipsilateral renal volume receiving 20 Gy can be used as partial organ dose constraint for SABR to targets in the upper abdomen. |
| Databáze: | OpenAIRE |
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