GEOMAGNETIC CHANGES AS A RISK FACTOR CAUSING OXIDATIVE STRESS IN HUMAN ERYTHROCYTES
| Autor: | T.G. Shcherbatyuk, Occupational Pathology, Semashko Str., Nizhny Novgorod, Russian Federation, L.V. Polyakova, E.S. Zhukova, M.A. Pozdnyakova, I.A. Umnyagina, V.V. Chernov, A.M. Irkaeva |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry human body catalase Risk factor (computing) medicine.disease_cause superoxide dismutase Earth's magnetic field Endocrinology geomagnetic disturbances Internal medicine heliobiology medicine Medicine Human erythrocytes magnetic sensitivity solar activity business kp-index Oxidative stress |
| Zdroj: | Analiz Riska Zdorovʹû, Iss 3, Pp 134-140 (2021) |
| ISSN: | 2542-2308 |
| DOI: | 10.21668/health.risk/2021.3.13.eng |
| Popis: | At present impacts exerted by heliogeophysic factors on different living organisms are being examined more and more intensely. Over the last decade, it has been detected that meteorological factors play an important role in formation of adap- tation mechanisms in living systems. Sun and earth interaction is also known to directly influence rheological properties of human blood, both in a healthy body and in case there are chronic non-communicable diseases. Given that, impacts exerted by “cosmic weather” on living organisms, people in particular, are a stimulus to perform profound studies on reactions oc- curring as a response to effects produced by solar and geomagnetic activity, first of all, solar flares and magnetic storms. At present the most widely used approach to determining influences exerted by the Earth magnetic field on biologi- cal systems involves searching for correlations between different parameters of living organisms functioning and geo- magnetic indexes. Our research goal was to assess dependence between enzymatic activity of antioxidant protection system, exemplified by superoxide dismutase (SOD) and catalase, and geomagnetic field disturbances. The research focused on examining blood samples taken from conditionally healthy volunteers living in Nizhniy Nov- gorod region. SOD and catalase activity were determined in blood erythrocytes with spectrophotometry. Geomagnetic dis- turbances force was determined as per planetary Kp-index value. The research established a statistically significant correlation between SOD and catalase activity and a value of geo- magnetic field disturbance; this correlation allows making an indirect assumption that geomagnetic conditions directly in- fluence superoxide radical production in a body. Therefore, a change in superoxide radical production is a way for the geomagnetic field to influence living organisms. Activation of free radical oxidation can make for both occurrence and more intense clinical course of several diseases (espe- cially cardiovascular and neuropsychic ones). So, in future it is advisable to assess reactivity of antioxidant protection sys- tem as a response to geomagnetic fluctuations in case there are pathologic changes in a body. |
| Databáze: | OpenAIRE |
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