Pulmonary nocardiosis: Risk factors and species distribution from a high burden centre
| Autor: | Marilyn M. Ninan, Manigandan Venkatesan, V. Balaji, Priscilla Rupali, Joy S. Michael |
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| Rok vydání: | 2022 |
| Předmět: |
Microbiology (medical)
General Immunology and Microbiology Immunology Nocardia Infections Microbiology Nocardia Infectious Diseases Immunology and Microbiology (miscellaneous) Risk Factors Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Humans Immunology and Allergy Immunosuppressive Agents Retrospective Studies |
| Zdroj: | Indian Journal of Medical Microbiology. 40:582-584 |
| ISSN: | 0255-0857 |
| DOI: | 10.1016/j.ijmmb.2022.08.010 |
| Popis: | Nocardiosis is a clinical and diagnostic challenge. This was a retrospective study carried out on cases of pulmonary nocardiosis presenting over 15 years. Clinical data was retrieved using the electronic patient records. Vitek MS 3.2 (MALDI TOF MS) was carried out on 22 isolates and sequencing on another 9 isolates. Of 71 patients presenting with pulmonary nocardiosis, 58 (81.6%) were on immunosuppressant therapy, 26 (46%) had a previous lung pathology, 11 (8%) were HIV associated. Disseminated disease was seen in 6 (8.4%). There were 8 (11.26%) deaths in this cohort of patients. Of 31/71 identified to species, the most common were Nocardia cyriacigeorgica (n = 11) followed by Nocardia farcinica (n = 9). |
| Databáze: | OpenAIRE |
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