A controlled study of use of patient-reported outcomes to improve assessment of late effects after treatment for head-and-neck cancer
| Autor: | Kirsten Frederiksen, Christoffer Johansen, Merete K Hansen, Anni Linnet Nielsen, Elo Andersen, Susanne Oksbjerg Dalton, Randi V. Karlsen, Trille Kristina Kjaer |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Research design medicine.medical_specialty Pediatrics 03 medical and health sciences 0302 clinical medicine Primary outcome Quality of life Surveys and Questionnaires Bayesian multivariate linear regression medicine Humans Radiology Nuclear Medicine and imaging Patient Reported Outcome Measures Survivors 030212 general & internal medicine business.industry Head and neck cancer Symptom burden Cancer Hematology Middle Aged medicine.disease Oncology Head and Neck Neoplasms Research Design 030220 oncology & carcinogenesis Quality of Life Physical therapy Female business After treatment Follow-Up Studies |
| Zdroj: | Radiotherapy and Oncology. 119:221-228 |
| ISSN: | 0167-8140 |
| Popis: | Background and purpose To test the effect of longitudinal feedback on late effects reported by survivors of head-and-neck cancer (HNC) to clinicians during regular follow-up. Material and methods A total of 266 participants were sequentially assigned to either control or intervention group and filled in electronic versions of the EORTC QLQ C-30, H&N35, HADS and a study-specific list of symptoms at up to two consecutive follow-up visits. Participants' symptoms displayed according to severity were provided to the clinician for the intervention group but not for the control group. Linear mixed-effects models were used to examine the number of symptoms assessed by clinicians (primary outcome). Multivariate linear regression models examined participants' long-term symptom control and QoL (secondary outcome). Results More symptoms were assessed by clinicians in the intervention group at all three visits ( P P = 0.04). No effect was observed on most patient outcomes. When prompted by patient-reported outcomes at consultations, clinicians and patients were in better agreement about the occurrence of severe symptoms at all three visits. Conclusion Timely patient-reported outcomes to clinicians in routine follow-up of HNC survivors enhanced clinicians' rates of assessment of late symptoms. Giving reports of patient-reported outcome to clinicians had limited impact on participants' QoL or symptom burden. |
| Databáze: | OpenAIRE |
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