Azalide 3,6-ketals: antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analogues

Autor:	Sheryl L. Santoro, Cheng Hengmiao, Martha L. Minich, Peter Bertinato, Subas M. Sakya, Melani Suarez-Contreras, Bryan Pratt, Camilla D. Bertsche, Shigeru F. Hayashi, David M. George, Barbara J. Kamicker, Kristin Marie Lundy, Ziegler Carl B
Rok vydání:	2003
Předmět:	Staphylococcus aureus Pasteurella multocida Stereochemistry animal diseases Clinical Biochemistry Pharmaceutical Science Cattle Diseases Microbial Sensitivity Tests Azalide medicine.disease_cause Biochemistry Chemical synthesis Gonadotropin-Releasing Hormone chemistry.chemical_compound Mice Structure-Activity Relationship Heterocyclic Compounds Drug Discovery otorhinolaryngologic diseases medicine Animals Pasteurellosis Pneumonic Molecular Biology Mastitis Bovine Antibacterial agent chemistry.chemical_classification Aryl Organic Chemistry Acetal Anti-Bacterial Agents chemistry Molecular Medicine Cattle Female Antibacterial activity Lactone medicine.drug
Zdroj:	Bioorganicmedicinal chemistry letters. 13(7)
ISSN:	0960-894X
Popis:	Aryl and hetero aryl substituted 3,6-ketals of 15-membered azalide analogues were synthesized and were found to have potent in vitro antibacterial activity against veterinary pathogens, including Staphylococcus aureus and Pasteurella multocida.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caacad70d869e31f2ce5a22d2adfb70 https://pubmed.ncbi.nlm.nih.gov/12657285 Zobrazit plný text záznamu Full Text from ScienceDirect