Does the timing of surgery for breast cancer in relation to the menstrual cycle or geomagnetic activity affect prognoses of premenopausal patients?
Autor: | Masazumi Eriguchi, Hironobu Yanagie, Yasutaka Takeda, I. Yoshizaki |
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Rok vydání: | 2003 |
Předmět: |
Adult
medicine.medical_specialty Time Factors media_common.quotation_subject Mammary gland Breast Neoplasms Disease Luteal phase Affect (psychology) Magnetics Breast cancer Japan Recurrence Follicular phase medicine Humans Menstrual Cycle Menstrual cycle media_common Pharmacology business.industry Cancer General Medicine Middle Aged medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Premenopause Female business |
Zdroj: | Biomedicine & Pharmacotherapy. 57:96-103 |
ISSN: | 0753-3322 |
Popis: | We examined the records in 36 breast cancer patients treated between 1990 and 2001, and compared them for relapse-free survival with reference to the phases of menstrual cycle defined by Hrushesky et al. and Senie et al. During the follow-up period, seven patients suffered a relapse and one died of another disease without relapsed breast cancer. The recurrence rate and relapse-free survival were not significantly different with the menstrual timing of surgery. However, patients with early breast cancer operated during the follicular phase and those with advanced breast cancer resected during the luteal phase appeared to show better prognosis than corresponding controls operated during the other phases. On the other hand, the correlation between geomagnetic activity and prognosis of breast cancer was also investigated. High geomagnetic activity during operation significantly affected the prognosis of the disease in an adverse fashion. This adverse influence was more marked in the patients operated during the luteal period. Since the menstrual cycle has no clear relation to the prognosis of breast cancer, the geomagnetic activity might affect them via other pathways than the menstrual cycle. |
Databáze: | OpenAIRE |
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