Effect of Carbamazepine Treatment on EEG Changes Induced by Different Cortical Activation Patterns in Newly Referred Epileptic Patients

Autor: Gian Luigi Gigli, N. Stefani, F. Stefanini, M. Sabbadini, Giorgio Bernardi, Maria Grazia Marciani
Rok vydání: 1992
Předmět:
Zdroj: Scopus-Elsevier
ISSN: 1423-0224
0302-282X
DOI: 10.1159/000118841
Popis: Sixteen epileptic patients suffering from focal epilepsy who underwent anti-epileptic drug treatment with carbamazepine (CBZ) for the first time were studied. The EEG was recorded at rest with eyes closed, during blocking reaction (BR), fixation (FIX) and mental arithmetic tasks. The computerized EEG study, performed before and after CBZ therapy, utilized spectral analysis. Data underwent statistical evaluation through Anova and correlation analysis. The parameters evaluated were the mean frequency and the mean absolute and relative power. The results have shown that after CBZ treatment there is a decrease in the alpha reactivity during BR and FIX, while a significant increase in beta activity was observed during all tasks. The effect of CBZ therapy on EEG activity during cortical activation patterns are discussed.
Databáze: OpenAIRE