Effect of Carbamazepine Treatment on EEG Changes Induced by Different Cortical Activation Patterns in Newly Referred Epileptic Patients
Autor: | Gian Luigi Gigli, N. Stefani, F. Stefanini, M. Sabbadini, Giorgio Bernardi, Maria Grazia Marciani |
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Rok vydání: | 1992 |
Předmět: |
Adult
Male medicine.medical_specialty Elementary cognitive task medicine.medical_treatment Electroencephalography Epilepsy Text mining medicine Humans Evoked Potentials Problem Solving Biological Psychiatry Cerebral Cortex medicine.diagnostic_test business.industry Signal Processing Computer-Assisted Carbamazepine medicine.disease Surgery Psychiatry and Mental health Electrophysiology Neuropsychology and Physiological Psychology Anticonvulsant Anesthesia Female Analysis of variance Arousal Psychology business medicine.drug |
Zdroj: | Scopus-Elsevier |
ISSN: | 1423-0224 0302-282X |
DOI: | 10.1159/000118841 |
Popis: | Sixteen epileptic patients suffering from focal epilepsy who underwent anti-epileptic drug treatment with carbamazepine (CBZ) for the first time were studied. The EEG was recorded at rest with eyes closed, during blocking reaction (BR), fixation (FIX) and mental arithmetic tasks. The computerized EEG study, performed before and after CBZ therapy, utilized spectral analysis. Data underwent statistical evaluation through Anova and correlation analysis. The parameters evaluated were the mean frequency and the mean absolute and relative power. The results have shown that after CBZ treatment there is a decrease in the alpha reactivity during BR and FIX, while a significant increase in beta activity was observed during all tasks. The effect of CBZ therapy on EEG activity during cortical activation patterns are discussed. |
Databáze: | OpenAIRE |
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