Accurate and Reproducible Mitral Valvular Blood Flow Measurement with Three?Directional Velocity?Encoded Magnetic Resonance Imaging
Autor: | Hildo J. Lamb, Mike G. Danilouchkine, Albert de Roos, Jeroen J. Bax, Jos J.M. Westenberg, Rob J. van der Geest, Johan H. C. Reiber, Gerda Labadie, Joost Doornbos, Michel I.M. Versteegh |
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Rok vydání: | 2004 |
Předmět: |
Adult
Male medicine.medical_specialty Phase (waves) Image processing Imaging Three-Dimensional medicine.artery Mitral valve Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Aged Observer Variation Aorta Radiological and Ultrasound Technology medicine.diagnostic_test Cardiac cycle business.industry Mitral Valve Insufficiency Reproducibility of Results Stroke Volume Magnetic resonance imaging Blood flow Middle Aged Magnetic Resonance Imaging medicine.anatomical_structure Flow (mathematics) Research Design Mitral Valve Female Radiology Cardiology and Cardiovascular Medicine business Blood Flow Velocity Echocardiography Transesophageal Biomedical engineering |
Zdroj: | Journal of Cardiovascular Magnetic Resonance. 6:767-776 |
ISSN: | 1532-429X 1097-6647 |
Popis: | A new method for quantifying the transvalvular flow through the mitral valve (MV) based on three-directional velocity-encoded magnetic resonance imaging (MRI) is presented. For thirty time phases during one cardiac cycle, the three-dimensional (3D) velocity vector field of the blood flow is reconstructed from the MRI measurement. Retrospectively, for each time phase, the MV-plane is indicated manually in the velocity data and the flow through this plane is determined, representing the MV flow. Measurements are performed in 10 healthy volunteers. The new method is compared to the conventional, one-directional velocity-encoded MRI method for which an acquisition plane is positioned at the mitral valve at end-systole and remains fixed during the acquisition. The flow measurements with the new method correlate very well with the flow measured in the aorta (r(p)=0.92, p0.01), whereas the conventional method shows no statistically significant correlation (r(p)=0.15, p=0.68). The low differences between the flow measured at the MV and the flow in the aorta proves high accuracy of the new method. Also, the new method shows very low intra- and interobserver variation, proving the high reproducibility. Three-directional velocity-encoded MRI is a patient-friendly and easy-to-use method suitable for quantifying accurately and reproducibly the transvalvular MV flow. |
Databáze: | OpenAIRE |
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