Effects of pyrolytic carbon on postoperative adhesion formation in rats
| Autor: | İlhami Sürer, Cüneyt Atabek, Ahmet Guven, Emin Oztas, Haluk Öztürk, Suzi Demirbag, Narter Yesildaglar |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Uterus Adhesion (medicine) Biocompatible Materials Tissue Adhesions Peritoneal Diseases Lesion Postoperative Complications Animals Medicine Ketamine Pyrolytic carbon Rats Wistar Uterine Diseases Tissue Adhesion Histocytochemistry business.industry Obstetrics and Gynecology General Medicine medicine.disease Carbon Rats Surgery medicine.anatomical_structure Female Zirconium Electrocauterization medicine.symptom business Wound healing medicine.drug |
| Zdroj: | Archives of Gynecology and Obstetrics. 279:11-15 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-008-0649-9 |
| Popis: | Peritoneal adhesion is a consequence of wound healing that sometimes causes severe postoperative complications. Despite all the preventive measures and agents, adhesions have still not been eliminated completely. The aim of this study was to evaluate the effects of pyrolytic carbon on the development of postoperative peritoneal and uterine tube adhesions. Twenty female Wistar–Albino type rats were used in this study. The rats were divided into two groups: treatment and control groups. After ketamine anaesthesia (50 mg/kg IM), a lower midline abdominal incision was performed and a standard uterine lesion was created by electrocauterization. In the study group, pyrolytic carbon was applied to the surface of the uterus and no additional procedure was applied in the control group. After 2 weeks, all of the rats were killed and uterine adhesions were staged according to the Leach scoring system. In the control group, the total adhesion score was 8.8 ± 0.42. In the study group, the total adhesion score was 3.3 ± 1.49, significantly lower than that in the control group (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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