Reversal and remission of T2DM - an update for practitioners

Autor: Lina Shibib, Mo Al-Qaisi, Ahmed Ahmed, Alexander D Miras, David Nott, Marc Pelling, Stephen E Greenwald, Nicola Guess
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Endocrinology
Diabetes and Metabolism
bariatric surgery
TYPE-2 DIABETES-MELLITUS
Y GASTRIC BYPASS
behaviour change
BETA-CELL FUNCTION
CARDIOVASCULAR RISK-FACTORS
Humans
Pharmacology (medical)
Obesity
LAPAROSCOPIC SLEEVE GASTRECTOMY
LOW-FAT DIET
NEUROMUSCULAR ELECTRICAL-STIMULATION
Life Style
orlistat
Science & Technology
GLUCAGON-LIKE PEPTIDE-1
low carbohydrate
behaviour change
diabetes reversal
diabetes remission
Public Health
Environmental and Occupational Health
very low calorie
LOW-CARBOHYDRATE-DIET
1103 Clinical Sciences
Hematology
General Medicine
LOW-CALORIE DIET
electrical muscle stimulation
diabetes remission
Treatment Outcome
Peripheral Vascular Disease
Diabetes Mellitus
Type 2
Cardiovascular System & Hematology
Cardiovascular System & Cardiology
very low energy
diabetes reversal
weight loss
Cardiology and Cardiovascular Medicine
Life Sciences & Biomedicine
low carbohydrate
Popis: Over the past 50 years, many countries around the world have faced an unchecked pandemic of obesity and type 2 diabetes (T2DM). As best practice treatment of T2DM has done very little to check its growth, the pandemic of diabesity now threatens to make health-care systems economically more difficult for governments and individuals to manage within their budgets. The conventional view has been that T2DM is irreversible and progressive. However, in 2016, the World Health Organization (WHO) global report on diabetes added for the first time a section on diabetes reversal and acknowledged that it could be achieved through a number of therapeutic approaches. Many studies indicate that diabetes reversal, and possibly even long-term remission, is achievable, belying the conventional view. However, T2DM reversal is not yet a standardized area of practice and some questions remain about long-term outcomes. Diabetes reversal through diet is not articulated or discussed as a first-line target (or even goal) of treatment by any internationally recognized guidelines, which are mostly silent on the topic beyond encouraging lifestyle interventions in general. This review paper examines all the sustainable, practical, and scalable approaches to T2DM reversal, highlighting the evidence base, and serves as an interim update for practitioners looking to fill the practical knowledge gap on this topic in conventional diabetes guidelines.
Databáze: OpenAIRE
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