What Have We Learned about the Use of Cytosorb Adsorption Columns?
| Autor: | Pan Xie, yuanyuan xie, Ghada Ankawi, Bo Yang, Claudio Ronco, Yun Xie |
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| Rok vydání: | 2019 |
| Předmět: |
Extracorporeal Circulation
medicine.medical_specialty medicine.medical_treatment Inflammatory response 030232 urology & nephrology Therapeutics 030204 cardiovascular system & hematology Plasma filtration Immunomodulation 03 medical and health sciences 0302 clinical medicine Adsorption Extracorporeal blood purification medicine High volume hemofiltration Humans Renal replacement therapy Intensive care medicine business.industry Hematology General Medicine Evidence-based medicine Nephrology Treatment strategy Hemofiltration business |
| Zdroj: | Blood Purification. 48:196-202 |
| ISSN: | 1421-9735 0253-5068 |
| DOI: | 10.1159/000500013 |
| Popis: | Extracorporeal blood purification techniques have emerged and evolved in the recent years as a potential therapy for the purpose of immunomodulation in acute conditions like sepsis. Understanding the extent of immune system dysregulation involved in the pathophysiology of these conditions, resulted in the development of such treatment strategies aiming at restoring a balanced inflammatory response. Beyond conventional continuous renal replacement therapy, high volume hemofiltration, high cut-off membranes, adsorption alone and coupled plasma filtration adsorption are well-described techniques in the literature. The evidence to support their routine use, however, is conflicting and insufficient at this stage. Despite the low-quality level of evidence in favor of utilizing these techniques, studies to further explore their effectiveness, safety, and potential novel applications, continue to evolve. Our review aims at focusing on adsorption therapy, particularly using the adsorption columns Cystosorb. |
| Databáze: | OpenAIRE |
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