| Autor: |
Xiu-Wu Bian, Xia Zhang, Hsiang-Fu Kung, Jeremy N. Rich, You-Hong Cui, Cheng Qian, Qing Liu, Wen-Juan Fu, Qing-Liang Wang, Wei Cui, Sen-Lin Xu, Lang Yang, Bin Wang, Yi-Fang Ping, Jing Yang, Li-Ru He, Xiao-Jun Yang, Shi-Cang Yu, Dan Xie, Chuan Xu |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22394166 |
| Popis: |
Supplementary Figures 1-8 PDF file 1850K, Supplementary Figure 1. LACSLCs derived from A549 and H358 cell lines; Supplementary Figure 2. Sphere LACSLCs derived from A549 cell line expressed high levels of CSLCs transcription factors including SOX2 and POU5F1 with low expression of differentiated markers CK8/CK18;Supplementary Figure 3. Immunofluorescence staining of CD133 and ALDH1A1;Supplementary Figure 4. Correlation of IGF-1R and ALDH1A1 with poor DSS in LAC patients;Supplementary Figure 5. Insulin signaling/IGF pathway is highly correlated with expression genes in LACSLCs;Supplementary Figure 6. Disruption of IGF-1R signaling pathway inhibits the self-renewal and the tumorigenic potential of human LACSLCs;Supplementary Figure 7. MEK inhibitor PD98059 has no effect on POU5F1; Expression of IGF-1, �-catenin and POU5F1 in fresh LAC specimens and A549 LACSLCs |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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