Molecular (ticks) and serological (humans) study of Crimean-Congo hemorrhagic fever virus in the Iberian Peninsula, 2013–2015
| Autor: | Sonia Santibáñez, Agustín Muñoz-Sanz, Lourdes Romero, José A. Oteo, Lara García-Álvarez, Francisco J. Márquez, José María Eiros, Aránzazu Portillo, Ana M. Palomar |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Ixodidae Hyalomma marginatum 030106 microbiology 030231 tropical medicine Cattle Diseases Biology Tick Antibodies Viral Virus Serology 03 medical and health sciences 0302 clinical medicine Seroepidemiologic Studies Rhipicephalus bursa parasitic diseases Animals Humans 030212 general & internal medicine Geography Medical Fluorescent Antibody Technique Indirect Tick Bites biology.organism_classification Virology Tick Infestations Immunoglobulin G Hemorrhagic Fever Virus Crimean-Congo biology.protein Arachnid Vectors Cattle Hemorrhagic Fever Crimean Viral disease Antibody Crimean Congo hemorrhagic fever virus |
| Zdroj: | Enfermedades Infecciosas y Microbiología Clínica. 35:344-347 |
| ISSN: | 0213-005X |
| Popis: | Introduction Crimean-Congo hemorrhagic fever (CCHF) is a viral disease, mainly transmitted through tick bite, of great importance in Public Health. In Spain, Crimean-Congo hemorrhagic fever virus (CCHFV) was detected for the first time in 2010 in Hyalomma lusitanicum ticks collected from deer in Caceres. The aim of this study was to investigate the presence of CCHFV in ticks from Caceres, and from other Spanish areas, and to evaluate the presence of antibodies against the virus in individuals exposed to tick bites. Methods A total of 2053 ticks (1333 Hyalomma marginatum , 680 H. lusitanicum and 40 Rhipicephalus bursa ) were analyzed using molecular biology techniques (PCR) for CCHFV detection. The determination of specific IgG antibodies against CCHFV in 228 serum samples from humans with regular contact with ticks (at risk of acquiring the infection) was performed by indirect immunofluorescence assay. Results The CCHFV was not amplified in ticks, nor were antibodies against the virus found in the serum samples analyzed. Conclusion The absence of the CCHFV in the ticks studied and the lack of antibodies against the virus in individuals exposed to tick bites would seem to suggest a low risk of acquisition of human infection by CCHFV in Spain. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|