Sialylated endogenous glycoconjugates in plant cells
| Autor: | Kazuhito Fujiyama, Lokesh Joshi, Miti Shah, C. Robert Flynn |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Glycosylation
Glycoconjugate Arabidopsis Biomedical Engineering Asialoglycoproteins Bioengineering Endogeny Biology Applied Microbiology and Biotechnology chemistry.chemical_compound Arabidopsis thaliana chemistry.chemical_classification fungi food and beverages Plant cell biology.organism_classification N-Acetylneuraminic Acid carbohydrates (lipids) Enzyme chemistry Biochemistry Cell culture cardiovascular system Molecular Medicine Glycoconjugates Biotechnology |
| Zdroj: | Nature Biotechnology. 21:1470-1471 |
| ISSN: | 1546-1696 1087-0156 |
| DOI: | 10.1038/nbt912 |
| Popis: | Bioengineered plants are emerging as promising systems for the production of therapeutically valuable proteins. It has been commonly accepted that plants do not perform mammalian-like post-translational modifications, particularly sialylation of glycoconjugates, and no evidence has previously been reported to suggest that they have such capabilities. Here we report the presence of sialylated glycoconjugates in suspension-cultured cells of Arabidopsis thaliana and suggest that a genetic and enzymatic basis for sialylation exists in plants. |
| Databáze: | OpenAIRE |
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