High‐resolution impedance manometry characterizes the functional role of distal colonic motility in gas transit
| Autor: | Reizal Mohd Rosli, Simon J. H. Brookes, Phil G. Dinning, Raghu Kumar, Paul T. Heitmann, Taher Omari, Lukasz Wiklendt, Lyn Maslen, David Wattchow, Marcello Costa |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Insufflation medicine.medical_specialty Contraction (grammar) Colon Manometry Physiology Rectum High resolution Descending colon Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Electric Impedance medicine Humans Gastrointestinal Transit Aged Endocrine and Autonomic Systems business.industry Gastroenterology Sigmoid colon Middle Aged medicine.anatomical_structure Volume (thermodynamics) 030220 oncology & carcinogenesis Cardiology Female 030211 gastroenterology & hepatology Gastrointestinal Motility business Colonic motility |
| Zdroj: | Neurogastroenterology & Motility. 34 |
| ISSN: | 1365-2982 1350-1925 |
| Popis: | BACKGROUND The colonic motor patterns associated with gas transit are poorly understood. This study describes the application of high-resolution impedance manometry (HRiM) in the human colon in vivo to characterize distal colonic motility and gas transit; (a) after a meal and (b) after intraluminal gas insufflation into the sigmoid colon. METHODS HRiM recordings were performed in 19 healthy volunteers, with sensors positioned from the distal descending colon to the proximal rectum. Protocol 1 (n = 10) compared pressure and impedance prior to and after a meal. Protocol 2 (n = 9) compared pressure and impedance before and after gas insufflation into the sigmoid colon (60 mL total volume). KEY RESULTS Both the meal and gas insufflation resulted in an increase in the prevalence of the 2-8/minute "cyclic motor pattern" (meal: (t(9) = -6.42, P |
| Databáze: | OpenAIRE |
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