Analyzing the effect of laparoscopy duration time on peroperative gastroesophageal reflux
| Autor: | Hakan Taşkınlar, İsa Kıllı, Caner İsbir, Gökhan Berktuğ Bahadır, Dilek Yünlüel, Ali Nayci, Ulku Comelekoglu |
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| Rok vydání: | 2019 |
| Předmět: |
Laparoscopic surgery
Time Factors medicine.medical_treatment Trendelenburg position Rat model laparoscopy Abdominal cavity Article Laparotomy medicine Animals Rats Wistar Laparoscopy medicine.diagnostic_test business.industry rat model Reflux General Medicine Rats Disease Models Animal Catheter medicine.anatomical_structure Gastroesophageal reflux Anesthesia Gastroesophageal reflux laparoscopy rat mode Intra-Abdominal Hypertension business Pneumoperitoneum Artificial |
| Zdroj: | Volume: 49, Issue: 2 639-643 Turkish Journal of Medical Sciences |
| ISSN: | 1300-0144 1303-6165 |
| Popis: | Background/aim: Intraabdominal pressure (IAP) is one of the main reasons for gastroesophageal reflux (GER). This study investigates whether IAP during laparoscopic surgery leads to GER in a time-dependent manner.Materials and methods: In a laparoscopy model, 15 mmHg IAP was created in 8 Wistar albino rats in the Trendelenburg position (TP). A 5 mm laparotomy was performed in the left lower abdominal region, and a 6 Fr catheter was placed intraabdominally. Air was insufflated into the abdominal cavity, and the pressure was kept constant at 15 mmHg. Esophageal pH alterations were measured by pH sticks for 4 h every 30 min.Results: The basal median esophageal pH value was 9 (8-10), the value after placing the catheter was 9 (7-10) (P = 0.47), and the median pH value after placing the subjects in TP was 9 (8-10) (P = 0.70). In our experimental model, esophageal pH values were found to decrease significantly at the 150th minute in TP and at 15 mmHg IAP (P < 0.05). Two rats died: one at the 120th minute and the other at the 240th minute (P > 0.05).Conclusion: Esophageal pH values decreased and continued to remain low following IAP increase and TP in this experimental rat model. Prolonged laparoscopic procedures can particularly lead to GER that requires instant recognition and rapid and appropriate intervention. |
| Databáze: | OpenAIRE |
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