Ophthalmic Screening in Patients with Coronavirus Disease 2019: A Prospective Cohort Study
| Autor: | Markus Tschopp, Anna Conen, Tim J Enz, Marcel N. Menke, Sebastian Haubitz, Viviane J. Guignard, Anthia Papazoglou |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
retina
Intraocular pressure medicine.medical_specialty genetic structures lcsh:Medicine Article optic nerve Ophthalmoscopy 03 medical and health sciences 0302 clinical medicine Ophthalmology medicine 030212 general & internal medicine Prospective cohort study Pathological Retina medicine.diagnostic_test SARS-CoV-2 business.industry lcsh:R ocular involvement COVID-19 General Medicine eye diseases medicine.anatomical_structure 030221 ophthalmology & optometry Optic nerve sense organs Animal studies business Optic disc |
| Zdroj: | Journal of Clinical Medicine, Vol 10, Iss 896, p 896 (2021) Journal of Clinical Medicine Volume 10 Issue 5 |
| ISSN: | 2077-0383 |
| DOI: | 10.3390/jcm10050896 |
| Popis: | Postmortem pathological examinations, animal studies, and anecdotal reports suggest that coronavirus disease 2019 (COVID-19) could potentially affect intraocular tissue. However, published evidence is scarce and conflicting. In our study, we screened 100 eyes of 50 patients hospitalized for COVID-19. Relevant medical and ophthalmological history was assessed as well as symptoms, laboratory results, specific treatments, clinical course, and outcome. Ophthalmic exams including assessment of best corrected visual acuity (BCVA), intraocular pressure (IOP), color perception, ocular motility, ophthalmoscopy as well as optical coherence tomography (OCT) of the macula and the optic disc was performed at hospital admission and 29 to 192 days later. Of the 50 patients included, 14 (28%) were female. Median age was 64.5 (range 29–90) years. COVID-19 severity was mild in 15 (30%), severe in 30 (60%), and critical in five cases (10%). At baseline, median BCVA was 0.1 (0–1.8) Logarithm of the Minimum Angle of Resolution (LogMAR) and median IOP was 16 (8–22) mmHg. At follow-up, no relevant changes in BCVA and IOP were documented. No signs of active intraocular inflammation or optic nerve affection were found and OCT findings were widely stable during the observation period. Our findings suggest that COVID-19 does not regularly affect intraocular tissue. |
| Databáze: | OpenAIRE |
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