Identification of a human population infected with simian foamy viruses
| Autor: | Jennifer Brown, Shanmugam Vedapuri, Louisa E. Chapman, Walid Heneine, William M. Switzer, Matthias Schweizer, Dieter Neumann-Haefelin, Paul Sandstrom, Thomas M. Folks, Arifa S. Khan, Charles A. Schable, Nicholas W. Lerche |
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| Rok vydání: | 1998 |
| Předmět: |
Male
Sexual transmission Pan troglodytes viruses Population Simian foamy virus Simian Antibodies Viral Polymerase Chain Reaction General Biochemistry Genetics and Molecular Biology Virus Occupational Exposure Zoonoses Chlorocebus aethiops Prevalence Animals Humans Lymphocytes education Spumavirus Phylogeny education.field_of_study biology Transmission (medicine) Primate Diseases General Medicine biology.organism_classification Macaca mulatta Virology Occupational Diseases Retroviridae Immunology African Green Monkey Papio Retroviridae Infections |
| Zdroj: | Nature Medicine. 4:403-407 |
| ISSN: | 1546-170X 1078-8956 |
| Popis: | Studying the transmission of simian retroviruses to humans can help define the importance of these infections to public health. We identified a substantial prevalence (4/231, 1.8%) of infection with simian foamy viruses (SFV) among humans occupationally exposed to nonhuman primates. Evidence of SFV infection included seropositivity, proviral DNA detection and isolation of foamy virus. The infecting SFV originated from an African green monkey (one person) and baboons (three people). These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections. |
| Databáze: | OpenAIRE |
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