Low number of fixed somatic mutations in a long-lived oak tree
| Autor: | Jérémie Voumard, Marc Robinson-Rechavi, Michel Schneider, Lance E. Keller, Emanuel Schmid-Siegert, Michel Jaboyedoff, Sandra Calderon, Christian S. Hardtke, Laurent Farinelli, Caroline Gouhier-Darimont, Pietro Cattaneo, Christian Fankhauser, John R. Pannell, Alexandre Reymond, Frédéric Schütz, Marco Pagni, Namrata Sarkar, Christian Iseli, Ioannis Xenarios, Philippe Reymond, Jacqueline Chrast |
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| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
0301 basic medicine Mutation rate Plant stem cell Somatic cell Longevity Meristem Plant Science Biology medicine.disease_cause Genes Plant 01 natural sciences Genome Polymorphism Single Nucleotide Germline Trees 03 medical and health sciences Quercus Mutation Rate medicine Genetics Mutation Zygote fungi food and beverages 030104 developmental biology Plant Shoots 010606 plant biology & botany |
| Zdroj: | Nature plants. 3(12) |
| ISSN: | 2055-0278 |
| Popis: | Because plants do not possess a defined germline, deleterious somatic mutations can be passed to gametes, and a large number of cell divisions separating zygote from gamete formation may lead to many mutations in long-lived plants. We sequenced the genome of two terminal branches of a 234-year-old oak tree and found several fixed somatic single-nucleotide variants whose sequential appearance in the tree could be traced along nested sectors of younger branches. Our data suggest that stem cells of shoot meristems in trees are robustly protected from the accumulation of mutations. |
| Databáze: | OpenAIRE |
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