Dobutamine stress tagging and gradient-echo imaging for detection of coronary heart disease at 3 T
Autor: | T Sommer, T Gampert, H. H. Schild, J Mazraeh, C. P. Naehle, K. Strach, Daniel Thomas, Carsten H. Meyer |
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Rok vydání: | 2011 |
Předmět: |
Male
medicine.medical_specialty Cardiotonic Agents Image quality Stress testing Coronary Disease Coronary Angiography Sensitivity and Specificity Coronary artery disease Dobutamine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Full Paper business.industry Ethics committee General Medicine Dobutamine stress Middle Aged medicine.disease Coronary heart disease Gradient echo imaging Cardiology Feasibility Studies Female Radiology business Echocardiography Stress medicine.drug |
Zdroj: | The British Journal of Radiology. 84:44-50 |
ISSN: | 1748-880X 0007-1285 |
Popis: | Objective: The purpose of this study was to evaluate the feasibility and diagnostic accuracy of a combined spoiled gradient-echo (sGRE) andtagged gradient-echo (SPAMM-GRE) protocol for detection of coronary artery disease (CAD) during high-dose dobutamine stress at 3T. Method: The study protocol was approved by the local ethics committee. For stress testing, a standard high-dose dobutamine protocol was employed. Image quality at the highest stress level and diagnostic accuracy of the sGRE and SPAMM-GRE sequences were comparedThe final study population consisted of 37 patients. Results: The mean image quality score was 2.6i0.6 for the sGRE sequence and 2.4i0.6 for the SPAMM-GRE sequence (p.0.05). Sensitivity, specificity and diagnostic accuracy were 0.81, 0.86, 0.84 and 0.88, 0.86, 0.86 for the sGRE and SPAMM-GRE, respectively. In three cases with new wall motion abnormalities (WMAs), detected by sGRE and SPAMM-GRE, WMAs were detected at a lower stress level by tagging. Conclusion: The combined sGRE and SPAMM-GRE high-dose dobutamine protocol at 3T is feasible and delivers good diagnostic accuracy. Tagging increases the sensitivity of high-dose dobutamine stress testing for detection of CAD and may allow for detection of new WMAs at lower stress levels compared with sGRE alone. |
Databáze: | OpenAIRE |
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