| Autor: |
Iori Nozaki, Natsumi Ishikawa, Yusuke Miyanari, Kazuma Ogawa, Ayako Tagawa, Sakura Yoshida, Masayuki Munekane, Kenji Mishiro, Akira Toriba, Morio Nakayama, Takeshi Fuchigami |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Bioconjugate chemistry. 33(11) |
| ISSN: |
1520-4812 |
| Popis: |
Survivin is overexpressed in most cancer cells but is rarely expressed in normal adult tissues. It is associated with poor prognosis and resistance to radiation therapy and chemotherapy. In this study, we designed and synthesized borealin-derived small peptides (Bor peptides) to function as survivin-targeting agents for the diagnosis and treatment of cancers. These peptides exhibited binding affinities for recombinant human survivin ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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