Stereotactic Lesion in the Forel's Field H: A 2-Years Prospective Open-Label Study on Motor and Nonmotor Symptoms, Neuropsychological Functions, and Quality of Life in Parkinson Disease
| Autor: | Osmar Moraes, Maria Sheila Guimarães Rocha, Maira Okada de Oliveira, Paul Rodrigo Reis, Carlos A. Bana e Costa, Paulo Roberto Terzian Filho, Fabio Godinho, Michel Magnin, Marivaldo Nascimento |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Unified Parkinson's disease rating scale Disease Neuropsychological Tests Motor symptoms Stereotaxic Techniques Lesion 03 medical and health sciences Cognition 0302 clinical medicine Rating scale Surveys and Questionnaires Internal medicine Tremor Humans Medicine Prospective Studies Gait Aged 030304 developmental biology 0303 health sciences business.industry Neuropsychology Parkinson Disease Middle Aged Dyskinesia Subthalamus Stereotaxic technique Quality of Life Female Surgery Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Neurosurgery. 85:E650-E659 |
| ISSN: | 1524-4040 0148-396X |
| DOI: | 10.1093/neuros/nyz039 |
| Popis: | BACKGROUND Stereotactic lesion in the Forel's field H (campotomy) was proposed in 1963 to treat Parkinson disease (PD) symptoms. Despite its rationale, very few data on this approach have emerged. Additionally, no study has assessed its effects on nonmotor symptoms, neuropsychological functions and quality of life. OBJECTIVE To provide a prospective 2-yr assessment of motor, nonmotor, neuropsychological and quality of life variables after unilateral campotomy. METHODS Twelve PD patients were prospectively evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS), the Dyskinesia Rating Scale and the Parkinson's disease quality of life questionnaire (PDQ39) before campotomy, and after 6 and 24 mo. Nonmotor, neuropsychiatric, neuropsychological and quality of life variables were assessed. The impact of PD on global health was also rated. RESULTS A significant reduction in contralateral rest tremor (65.7%, P |
| Databáze: | OpenAIRE |
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