High cortisol responses identify propensity for obesity that is linked to thermogenesis in skeletal muscle

Autor:	Iain J. Clarke, I. Ross Young, Brian L. Leury, T. Kevin Lee, Alexandra Rao, Zane B. Andrews, Belinda A. Henry, Justin C. St. John
Rok vydání:	2013
Předmět:	Leptin Hypothalamo-Hypophyseal System medicine.medical_specialty Hydrocortisone Blotting Western Pituitary-Adrenal System Real-Time Polymerase Chain Reaction Biochemistry Internal medicine Genetics medicine Animals Uncoupling protein Obesity Muscle Skeletal Molecular Biology Sheep business.industry Body Weight Malignant hyperthermia Skeletal muscle Thermogenesis medicine.disease Endocrinology medicine.anatomical_structure Postprandial Body Composition Female Energy Metabolism business Hypothalamic–pituitary–adrenal axis Biotechnology medicine.drug
Zdroj:	The FASEB Journal. 28:35-44
ISSN:	1530-6860 0892-6638
DOI:	10.1096/fj.13-238345
Popis:	Subjects characterized as cortisol high responders (HRs) consume more calories after stress, but it is unknown whether cortisol responsiveness predicts a propensity for obesity. Female sheep with either high or low cortisol responses to adrenocorticotropin (ACTH) were identified. Body composition was similar in HRs and cortisol low responders (LRs), but the HRs had greater (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5b84dc669fb17bdc052d6ca4bceed7 https://doi.org/10.1096/fj.13-238345 Zobrazit plný text záznamu Plný text