The potential effects of Ankaferd blood stopper and fibrin sealent on sleeve gastrectomy staple‑line healing: An experimental study
| Autor: | Tuna Bilecik, Alkan Sakar, Tahir Oruç, Burhan Mayir |
|---|---|
| Přispěvatelé: | İstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Bilecik, Tuna |
| Rok vydání: | 2019 |
| Předmět: |
obesity
Cancer Research Sleeve gastrectomy medicine.medical_specialty medicine.medical_treatment Anastomosis Group A Fibrin Group B Hydroxyproline chemistry.chemical_compound Immunology and Microbiology (miscellaneous) Medicine Ankaferd blood stopper biology business.industry Articles General Medicine fibrin sealent Surgery chemistry biology.protein laparoscopic sleeve gastrectomy Complication business |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2019.7842 |
| Popis: | Staple-line bleeding and leakage is a life-threatening complication in obese patients following laparoscopic sleeve gastrectomy. The aim of this study was to examine the potential effects of Ankaferd blood stopper (ABS) and Fibrin Sealant (FS; Tisseel (R)) on sleeve gastrectomy staple-line healing in an experimental animal model. A total of 30 Wistar albino female rats were divided into three groups and were subjected to sleeve gastrectomy with linear stapling. Group A (control group) had nothing administered, Group B was administered FS on the staple-line, and Group C was administered ABS on the staple-line following sleeve gastrectomy. After sacrifice on postoperative day 5, anastomotic burst pressure, tissue hydroxyproline levels and histopathological parameters were measured. The results revealed that group C had the highest mean bursting pressure level. However, the values of this parameter were not found to differ significantly between the groups (P>0.05). Group B and C had a similar hydroxyproline levels but increased compared with group A (P |
| Databáze: | OpenAIRE |
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