Novel Antiplatelet Therapies for Atherothrombotic Diseases
| Autor: | Deepak L. Bhatt, Arjun Majithia |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Acute coronary syndrome Arterial disease ATVB in Focus: From Cells to the Clinic: Progress in the Development of Novel Therapeutics for ATVB Diseases Disease acute coronary syndrome Ischemia cardiovascular disease medicine Humans Thrombophilia cardiovascular diseases Myocardial infarction Intensive care medicine thrombosis Atherothrombotic disease business.industry Atherosclerosis medicine.disease Thrombosis myocardial infarction Hemostasis Concomitant hemostasis Cardiology and Cardiovascular Medicine business Platelet Aggregation Inhibitors circulatory and respiratory physiology |
| Zdroj: | Arteriosclerosis, Thrombosis, and Vascular Biology |
| ISSN: | 1524-4636 1079-5642 |
| DOI: | 10.1161/atvbaha.118.310955 |
| Popis: | Antiplatelet therapies are an essential tool to reduce the risk of developing clinically apparent atherothrombotic disease and are a mainstay in the therapy of patients who have established cardiovascular, cerebrovascular, and peripheral artery disease. Strategies to intensify antiplatelet regimens are limited by concomitant increases in clinically significant bleeding. The development of novel antiplatelet therapies targeting additional receptor and signaling pathways, with a focus on maintaining antiplatelet efficacy while preserving hemostasis, holds tremendous potential to improve outcomes among patients with atherothrombotic diseases. |
| Databáze: | OpenAIRE |
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