Organophosphate pesticide environmental exposure: analysis of salivary cholinesterase and carboxilesterase activities in preschool children and their mothers
| Autor: | Guillermo Sabino, Gladis Magnarelli, María Gabriela Rovedatti, Vanina Bulgaroni |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Passive smoking Argentina Physiology Management Monitoring Policy and Law medicine.disease_cause Carboxylesterase Toxicology chemistry.chemical_compound Young Adult Organophosphorus Compounds medicine Cholinesterases Humans Young adult Pesticides Saliva General Environmental Science Cholinesterase Carboxylesterase activity biology Organophosphate General Medicine Environmental exposure Environmental Exposure Pesticide Pollution chemistry Child Preschool biology.protein Environmental Pollutants Female |
| Zdroj: | Environmental monitoring and assessment. 184(5) |
| ISSN: | 1573-2959 |
| Popis: | A pilot study was conducted to evaluate the usefulness of salivary cholinesterase and carboxylesterase as biomarkers of exposure to environmental organophosphate pesticides. Ninety samples were obtained from women and 62 samples from their preschool-aged children who live near an agricultural area of the Upper Valley of the Negro River (Patagonia, Argentina) where pesticides are applied 6 months a year. Each participant donated two samples under similar conditions: one in the pre-exposure period and another during the pulverization period. Demographic information, potential confounders, and risk behaviors were registered. Active or passive smoking had no effect on these enzyme activities in either group. During the pulverization period, cholinesterase activity was not detectable in 76% of the children's samples and 23% of the mothers' samples. Comparing samples collected during the pulverization period with respect to the pre-pulverization period, the average mother and child cholinesterase activity decreased by 65.7% (p |
| Databáze: | OpenAIRE |
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