Postoperative renal functional changes assessed by 99mTc-DTPA scintigraphy and predictive factors after miniaturized percutaneous nephrolithotomy and retrograde intrarenal surgery: An observational 1-year follow-up study
| Autor: | Juhyun Park, Hwancheol Son, Sangjun Yoo, Sung Yong Cho, Seung Hoon Ryang, Jae Hyun Jung, Hyeon Jeong, Min Chul Cho |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
urinary calculi Urology medicine.medical_treatment 030232 urology & nephrology kidney function tests Renal function 1 year follow up Scintigraphy Logistic regression lcsh:RC870-923 03 medical and health sciences chemistry.chemical_compound kidney calculi 0302 clinical medicine Medicine Percutaneous nephrolithotomy Creatinine medicine.diagnostic_test business.industry Perioperative lcsh:Diseases of the genitourinary system. Urology Surgery minimally invasive surgical procedures chemistry 030220 oncology & carcinogenesis Observational study business |
| Zdroj: | Investigative and Clinical Urology, Vol 61, Iss 1, Pp 59-66 (2020) |
| ISSN: | 2466-0493 |
| Popis: | Purpose We evaluated the comparative effect of miniaturized percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) on perioperative kidney function by use of diethylenetriamine penta-acetic acid (99mTc-DTPA) scintigraphy and identified significant predictors associated with deterioration or amelioration of renal function after surgery. Materials and methods All 70 patients who underwent mini-PCNL or RIRS between 2012 and 2016 were monitored by 99mTc-DTPA scintigraphy preoperatively. Patients with abnormal renal function were monitored from 3 to 12 months postoperatively. Logistic regression analyses were conducted to estimate the predictors of aggravated renal dysfunction and improvement. Results The difference in preoperative renal function between the contralateral and the operative side was >10% in 57 patients (81.4%). Among those in the group with abnormal renal function, 40 (70.2%), 10 (17.5%), and 7 (12.3%) patients showed stability, deterioration, and improvement in renal function at postoperative year 1, respectively. Functional changes did not differ according to the type of surgery. A high level of serum creatinine preoperatively (p=0.060) and a history of previous stone procedures (p=0.051) showed borderline significance for prediction of deterioration in renal function. Conclusions RIRS and mini-PCNL had similar effects and favorable outcomes on renal function during a 1-year follow-up period. High baseline serum creatinine levels and a history of procedures warrant careful attention. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|