Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination

Autor: M Roussel-Delvalez, Yazdan Yazdanpanah, Henri Migaud, Yves Mouton, C. Savage, Bernadette Roselé, Richard Stern, Eric Senneville, Laurence Legout
Rok vydání: 2006
Předmět:
Microbiology (medical)
Adult
Male
Bacilli
Ofloxacin
Gram-negative bacteria
Cephalosporins/administration & dosage/therapeutic use
Cefepime
Anti-Bacterial Agents/administration & dosage/therapeutic use
fluoroquinolone
joint infections
Microbiology
Ciprofloxacin/administration & dosage/therapeutic use
Bone Infection
Pharmacotherapy
Ciprofloxacin
Medicine
Humans
Ofloxacin/administration & dosage/therapeutic use
Adverse effect
Aged
Retrospective Studies
Aged
80 and over
biology
treatment
ddc:617
business.industry
Gram-Negative Bacterial Infections/drug therapy
Retrospective cohort study
General Medicine
Middle Aged
biology.organism_classification
Bone Diseases
Infectious
Bone infections
Anti-Bacterial Agents
Cephalosporins
Infectious Diseases
Bone Diseases
Infectious/drug therapy
Drug Therapy
Combination
Female
Joint Diseases
business
Gram-Negative Bacterial Infections
Enterobacter cloacae
Joint Diseases/drug therapy
medicine.drug
Zdroj: Clinical Microbiology and Infection, Vol. 12, No 10 (2006) pp. 1030-3
ISSN: 1198-743X
Popis: A 3-year retrospective study evaluated the effectiveness and safety of cefepime plus a fluoroquinolone for treating bone and joint infections caused by Gram-negative bacilli (GNB) in 28 patients. Intra-operative cultures yielded primarily Pseudomonas spp. and Enterobacter cloacae. Full recovery (cure) was observed in 79% of patients. There were no serious adverse effects and no resistant organisms were isolated. The results of the study confirmed the safety and effectiveness of cefepime combined with a fluoroquinolone for the treatment of bone and joint infections caused by Gram-negative bacilli.
Databáze: OpenAIRE
Externí odkaz: