Are increased levels of self-reported psychosocial stress, anxiety, and depression associated with fecundity?
| Autor: | Rajeshwari Sundaram, Cecilia Pyper, Germaine M. Buck Louis, Courtney D. Lynch, Kirsten J. Lum |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent media_common.quotation_subject Fertility Anxiety Article Social support Young Adult Pregnancy Surveys and Questionnaires medicine Humans Stress measures Psychiatry Prospective cohort study media_common business.industry Depression Obstetrics and Gynecology Social Support Odds ratio medicine.disease Reproductive Medicine Female Self Report medicine.symptom business Psychosocial Infertility Female Stress Psychological Demography |
| Zdroj: | Fertility and sterility. 98(2) |
| ISSN: | 1556-5653 |
| Popis: | Objective To assess the association between self-reported measures of stress, anxiety, depression, and related constructs and fecundity. Design Prospective cohort study of women trying to conceive. Setting United Kingdom. Patient(s) Three hundred thirty-nine women aged 18–40 years who were attempting to conceive. Intervention(s) Completed daily diaries for up to six cycles or until pregnancy was detected. For each cycle, stress biomarkers were measured and psychosocial questionnaires were completed. Main Outcome Measures(s) Fecundability odds ratios (FORs) and 95% confidence intervals were calculated using discrete time survival methods, and the day-specific probabilities of pregnancy were calculated using Bayesian statistical techniques. Result(s) Among the 339 women, 207 (61%) became pregnant during the study, 69 (20%) did not become pregnant, and 63 (19%) withdrew. After controlling for maternal age, parity, months trying to conceive before enrollment, smoking, caffeine use, and frequency of intercourse, we found no association between most psychosocial measures and FORs or the day-specific probabilities of pregnancy save for an increased FOR for women reporting higher versus lower levels of social support. Conclusion(s) Self-reported psychosocial stress, anxiety, and depression were not associated with fecundity. Any adverse effect of stress or psychological disturbance on fecundity does not appear to be detectable via the questionnaires administered. |
| Databáze: | OpenAIRE |
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