PET Imaging in Glioblastoma: Use in Clinical Practice
| Autor: | Karl-Josef Langen, Antoine Verger |
|---|---|
| Přispěvatelé: | BIRKER, Juliette, Service de Médecine Nucléaire [Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Institute of Neuroscience and Medicine [Jülich] (INM-1), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM), RWTH Aachen University |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment [INFO.INFO-IM] Computer Science [cs]/Medical Imaging [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine 030218 nuclear medicine & medical imaging [SDV.IB.MN] Life Sciences [q-bio]/Bioengineering/Nuclear medicine 03 medical and health sciences 0302 clinical medicine [INFO.INFO-IM]Computer Science [cs]/Medical Imaging Medicine Radiation treatment planning Grading (tumors) [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology medicine.diagnostic_test business.industry 18 F-FET PET Magnetic resonance imaging 11 C-MET PET Pet imaging 3. Good health Clinical trial Radiation therapy Positron emission tomography 030220 oncology & carcinogenesis 18 F-FDG PET Radiology Differential diagnosis business Glioblastoma 18 F-FDopa PET [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | Glioblastoma Glioblastoma, Codon Publications, pp.155-174, 2017, ⟨10.15586/codon.glioblastoma.2017.ch9⟩ Glioblastoma ISBN: 9780994438126 |
| DOI: | 10.15586/codon.glioblastoma.2017.ch9⟩ |
| Popis: | Positron emission tomography (PET) is a nuclear medicine imaging method with increasing relevance for the diagnosis, prognostication, and monitoring of glioblastomas. PET provides additional insight beyond magnetic resonance imaging (MRI) into the biology of gliomas, which can be used for noninvasive grading, differential diagnosis, delineation of tumor extent, planning of surgery, and radiotherapy and post-treatment monitoring. In clinical practice, two classes of radiotracers have been used predominantly for imaging purposes, namely glucose metabolism tracers and amino acid transport tracers. Both classes of tracers can provide information on grading and prognosis of gliomas, but amino acid tracers, which exhibit lower uptake in normal brain tissue, are better suited for delineation of tumor extent, treatment planning, or follow-up than 18F-2-fluoro- 2-deoxy-D-glucose (18F-FDG). Owing to the progress in PET imaging using radiolabeled amino acids in recent years, the Response Assessment in Neuro-Oncology (RANO) working group, an international effort to develop new standardized response criteria for clinical trials in brain tumors, has recently recommended amino acid PET as an additional tool in the diagnostic assessment of brain tumors. These developments as well as multimodality imaging should improve the diagnostic assessment of these tumors. |
| Databáze: | OpenAIRE |
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