An update on the clinical development of drugs to disable tumor vasculature

Autor:	Dietmar W. Siemann, David J. Chaplin
Rok vydání:	2007
Předmět:	business.industry Drug Discovery Investigational Drugs Cancer therapy Medicine Support system Tumor cells Pharmacology Tumor vasculature Bioinformatics business
Zdroj:	Expert Opinion on Drug Discovery. 2:1357-1367
ISSN:	1746-045X 1746-0441
Popis:	Traditional methods of improving cancer therapy have focused primarily on achieving increased tumor cell kill. However, more recent strategies involve impairing the nutritional support system of the tumor by targeting the tumor vasculature. Rapid developments in this field in recent years have resulted in the identification of a variety of potential targets and a large number of investigational drugs, many of which are now in clinical development. In the following paper the authors review vascular disrupting therapies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3ef62d38c26bf0064c3f644f06e6d7 https://doi.org/10.1517/17460441.2.10.1357 Zobrazit plný text záznamu