Faecal incontinence after chemoradiotherapy in anal cancer survivors: Long-term results of a national cohort
| Autor: | Lise Balteskard, Eva Hoff Wanderås, Gunilla Frykholm, Anne Gry Bentzen, Marianne Grønlie Guren, Olav Dahl, Barthold Vonen, Tom Wilsgaard |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Population Pelvis National cohort Cohort Studies Informed consent Internal medicine medicine Humans Anal cancer Radiology Nuclear Medicine and imaging Survivors education Aged Aged 80 and over Gynecology education.field_of_study Symptom management business.industry Chemoradiotherapy Hematology Long term results Middle Aged Anus Neoplasms medicine.disease humanities Radiation therapy Oncology Female business Fecal Incontinence |
| Zdroj: | Radiotherapy and Oncology. 108:55-60 |
| ISSN: | 0167-8140 |
| Popis: | To examine the prevalence and severity of faecal incontinence amongst anal cancer survivors after chemoradiotherapy.Anal cancer survivors from a complete, unselected, national cohort, minimum 2-years follow-up, were invited to a cross-sectional study. The St. Mark's incontinence score was used to evaluate occurrence and degree of faecal incontinence the last four weeks. The results were compared to age- and sex-matched volunteers from the general population.Of 199 invited survivors and 1211 volunteers, 66% and 21%, respectively, signed informed consent. The survivors had significantly higher St. Mark's score than the volunteers (mean 9.7 vs. 1.1, p0.001). Incontinence of stool of any degree was reported by 43% vs. 5% (OR 4.0, CI 2.73-6.01), and urgency was reported by 64% vs. 6% (OR 6.6, CI 4.38-9.90) of the survivors and volunteers, respectively. Only 29% of those with leakage of liquid stool used constipating drugs. Survivors of locally advanced tumours had a higher incontinence score (p0.01).Moderate to severe faecal incontinence is common amongst anal cancer survivors. Post-treatment follow-up should include the evaluation of continence, and incontinent survivors should be offered better symptom management and multidisciplinary approach if simple measures are insufficient. |
| Databáze: | OpenAIRE |
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