| Popis: |
Additional file 2: Figure S1. Tp1 multiple sequence alignment of amino acids from field samples from Rwanda together with Muguga, Kiambu, Serengeti, Chitongo, Nyakizu and Gikongoro vaccine isolates. The polymorphic amino acids are highlighted, and the epitope region is presented in boxes. Rwanda field samples (n = 11) show 100% epitope homology with the Muguga, Kiambu and Serengeti isolates. Only one sample was similar to Gikongoro isolate while the rest were 100% similar to Chitongo epitope. Figure S2. Tp2 multiple sequence alignment of amino acids from Rwanda field samples and the Muguga, Kiambu, Serengeti, Chitongo, Gikongoro and Nyakizu vaccine isolates. Field samples from Rwanda show similarity and variation across the 6 epitopes as compared to the vaccine stocks. Muguga, Kiambu and Serengeti epitopes compared to Chitongo, Gikongoro and Nyakizu are well represented in the Rwanda field samples. Majority of the samples exhibit epitope sequences that are different from Muguga, Kiambu and Serengeti sequences and only sample RW6 exhibited 100% epitope sequence homology with Chitongo vaccine isolate. The epitope region is presented in boxes and the polymorphic amino acids are highlighted. |
