When right differs from left : human limb directional asymmetry emerges during very early development
Autor: | Sofie Delen, Stefan Van Dongen, Liliane C. D. Wijnaendts, Clara M. A. ten Broek, Kristiina Heikinheimo, Frietson Galis, Jessica Bots |
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Přispěvatelé: | Pathology, Other Research |
Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Male
media_common.quotation_subject ta3111 Asymmetry Lower limb Fluctuating asymmetry Lateralization of brain function Bone and Bones Functional Laterality Developmental psychology Upper Extremity Arts and Humanities (miscellaneous) Humans Psychology General Psychology media_common ta313 Reproducibility of Results General Medicine Anatomy Adult life Limb bones Lower Extremity Aborted Fetus Female |
Zdroj: | Laterality : asymmetries of body, brain and cognition Laterality, 19(5), 591-601. Taylor and Francis Ltd. Van Dongen, S, Galis, F, Ten Broek, C, Heikinheimo, K, Wijnaendts, L C D, Delen, S & Bots, J 2014, ' When right differs from left: Human limb directional asymmetry emerges during very early development ', Laterality, vol. 19, no. 5, pp. 591-601 . https://doi.org/10.1080/1357650X.2014.891606 |
ISSN: | 1357-650X |
DOI: | 10.1080/1357650X.2014.891606 |
Popis: | The often observed directional asymmetry (DA) in human limb bones may have a genetic/developmental basis and/or could emerge from different mechanical loadings across sides due to handedness. Because behavioural lateralization in itself has a genetic basis, it has been suggested that DA in limbs could develop prenatally as a pre-adaptation to adult life. However, the presence of consistent differences in the size of left and right limb bones in early development is understudied. We study asymmetry in limb bones during early development (10-20 weeks of gestation) in a sample of 178 aborted foetuses. Statistically significant DA was found in several upper and lower limb bones, where the right-hand side was consistently larger than the left. We argue that this pattern is probably the consequence of developmental processes related to internal asymmetric positioning of organs. |
Databáze: | OpenAIRE |
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