Fractal approach to the rheology of concentrated cell suspensions

Autor: Andreea Iordan, Claude Verdier, Alain Duperray
Přispěvatelé: Verdier, Claude, Laboratoire de Spectrométrie Physique (LSP), Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), INSERM U823, équipe 8 (Immunologie Analytique des Pathologies Chroniques), Institut d'oncologie/développement Albert Bonniot de Grenoble (INSERM U823), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM)
Rok vydání: 2008
Předmět:
Materials science
Microfluidics
FOS: Physical sciences
Modulus
Thermodynamics
[SPI.MECA.MEFL] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph]
Nanotechnology
CHO Cells
Condensed Matter - Soft Condensed Matter
Models
Biological
Viscoelasticity
[SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph]
Quantitative Biology::Cell Behavior
Cricetulus
Fractal
fractal
Rheology
Cell Movement
Cricetinae
Cell Adhesion
suspension
Animals
[PHYS.MECA.MEFL] Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph]
Computer Simulation
[PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph]
Elasticity (economics)
Cell adhesion
Cells
Cultured
Viscoplasticity
Chinese hamster ovary cell
Elasticity
Culture Media
Condensed Matter::Soft Condensed Matter
yield stress
cells
Soft Condensed Matter (cond-mat.soft)
rheology
Stress
Mechanical
Zdroj: Physical Review E : Statistical, Nonlinear, and Soft Matter Physics
Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, 2008, 77, pp.011911
ISSN: 1550-2376
1539-3755
DOI: 10.1103/physreve.77.011911
Popis: Results on the rheological behavior of novel CHO cell suspensions in a large range of concentrations are reported. The concentration dependent yield stress and elastic plateau modulus are formalized in the context of fractal aggregates under shear, and quite different exponents are found as compared to the case of red blood cell suspensions. This is explained in terms of intrinsic microscopic parameters such as the cell-cell adhesion energy and cell elasticity but also the cell individual dynamic properties, found to correlate well with viscoelastic data at large concentrations (phi>0.5).
4 pages, 5 figures
Databáze: OpenAIRE
Externí odkaz: