Prospective evaluation of intestinal decompression in treatment of acute bowel obstruction from Crohn’s disease
| Autor: | Zhen Guo, Yi Li, Ruiqing Liu, Ke-Hao Wang, Shuaihua Qiao, Zhiming Wang, Jianfeng Gong, Weiming Zhu, Lei Cao |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Crohn’s disease
medicine.medical_specialty Crohn's disease medicine.diagnostic_test biology business.industry Decompression medicine.medical_treatment C-reactive protein Gastroenterology emergent surgery Disease medicine.disease Surgery Endoscopy Bowel obstruction acute bowel obstruction Intestinal decompression Laparotomy medicine biology.protein Intubation Original Article business |
| Zdroj: | Gastroenterology Report |
| ISSN: | 2052-0034 |
| DOI: | 10.1093/gastro/goz002 |
| Popis: | Background Conservative therapy for Crohn’s disease (CD)-related acute bowel obstruction is essential to avoid emergent surgery. The present study aimed to evaluate the efficacy of using a long intestinal decompression tube (LT) in treatment of CD with acute intestinal obstruction. Methods This is a prospective observational study. Comparative analysis was performed in CD patients treated with LT (the LT group) and nasogastric tube (the GT group). The primary outcome was the avoidance of emergent surgery. Additionally, predictive factors for failure of decompression and subsequent surgery were investigated. Results There were 27 and 42 CD patients treated with LT and GT, respectively, in emergent situations. Twelve (44.4%) patients using LT were managed conservatively without laparotomy, while only nine (21.4%) patients in the GT group were spared from emergent surgery (P 500 mL were predictors of unavoidable surgery (both P 0.05). Conclusions Endoscopic placement of LT could improve the emergent status in CD patients with acute bowel obstruction. The drainage output and changes in C-reactive protein after intubation could serve as practical predictive indices for subsequent surgery. Compared to traditional GT decompression, LT decompression was associated with fewer short-term complications and did not appear to affect long-term recurrence. |
| Databáze: | OpenAIRE |
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