Accumulation of Protoporphyrin Isomers I and III, and Multiple Decarboxylation Products of Uroporphyrin in a Case of Porphyria in a Slaughtered Pig
| Autor: | Joseph Hoorens, Stefan Roels, A Hassoun |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Pathology
medicine.medical_specialty Swine Decarboxylation Uroporphyrinogen III decarboxylase Protoporphyrins Kidney Bone and Bones Pathology and Forensic Medicine Porphyrias chemistry.chemical_compound Isomerism medicine Animals Uroporphyrins Swine Diseases General Veterinary medicine.disease Staining medicine.anatomical_structure Porphyria chemistry Female Protoporphyrin Lymph Nodes Bone marrow Lymph Tooth Abattoirs |
| Zdroj: | Journal of Veterinary Medicine Series A. 42:145-151 |
| ISSN: | 1439-0442 0931-184X |
| DOI: | 10.1111/j.1439-0442.1995.tb00366.x |
| Popis: | Pathological and biochemical examinations were made on tissues from a case of porphyria in a slaughtered pig. Bones, kidneys, teeth and lymph nodes showed a mahogany discoloration. Histologically, the pigment was negative on staining for iron (Gomori) and showed a strong red-orange fluorescence under UV light proving it to be porphyrin. Biochemical studies on the kidney, lymph nodes, bone and bone marrow revealed a 'mixed' erythropoietic protoporphyria-coproporphyria. This indicates that the case presented probably represented both a uroporphyrinogen decarboxylase and uroporphyrinogen-III-cosynthase dysfunction. |
| Databáze: | OpenAIRE |
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