Low-Grade Appendiceal Mucinous Neoplasms: A Single Institution Experience of 64 Cases With Clinical Follow-up and Correlation With the Current (Eighth Edition) AJCC Staging
| Autor: | Stacey Kim, Deepti Dhall, Richard B. Mertens, Alexandra Gangi, Brad D. Barrows, Mary Wong |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Pathologic staging Antineoplastic Agents Disease Pathology and Forensic Medicine Appendectomy Humans Medicine Single institution Neoplasm Staging Low Grade Appendiceal Mucinous Neoplasm business.industry Cancer Middle Aged Ajcc staging medicine.disease Adenocarcinoma Mucinous Appendix Treatment Outcome medicine.anatomical_structure Appendiceal Neoplasms Female Surgery Radiology Neoplasm Recurrence Local Anatomy business Progressive disease Follow-Up Studies |
| Zdroj: | International Journal of Surgical Pathology. 28:252-258 |
| ISSN: | 1940-2465 1066-8969 |
| Popis: | Background. In this single-institution study, we applied the current (eighth edition) American Joint Committee on Cancer pathologic staging criteria to 64 low-grade mucinous neoplasms of the appendix (LAMNs), examined their histopathologic features, and studied the patients’ clinical outcomes. Design. Sixty-four LAMNs, with a median follow-up of 52 months, were reviewed. Results. The distribution of pathologic stages was pTis (n = 39), pT3 (n = 1), pT4a (n = 5), pT4aM1a (n = 8), and pT4aM1b (n = 11). Recurrence was observed in only 2 patients (both with pT4aM1b disease), one of whom died of disease. All remaining patients were disease-free after a median clinical follow-up of 60 months. Conclusions. Our study confirms that pTis LAMNs have an excellent prognosis and suggests that pT4a and pT4aM1a LAMNs may also have a low risk of developing progressive disease. |
| Databáze: | OpenAIRE |
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