Comparison of Two Commercially Available Gamma Interferon Blood Tests for Immunodiagnosis of Tuberculosis
| Autor: | Vicente Ausina, José Domínguez, M. Angeles Jimenez, Cristina Prat, Silvia Blanco, Alicia Lacoma, Malú De Souza-Galvão, Neus Altet, Celia Milà, Juan Ruiz-Manzano, Irene Latorre |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Microbiology (medical) Tuberculosis Adolescent Clinical Biochemistry Immunology Mycobacterium tuberculosis Interferon-gamma Bacterial Proteins Tuberculosis diagnosis Antigen Gamma interferon medicine Humans Immunology and Allergy Interferon gamma Prospective Studies Child Aged Antigens Bacterial Mycobacterium bovis biology Tuberculin Test business.industry Clinical and Diagnostic Laboratory Immunology Middle Aged biology.organism_classification medicine.disease Virology Vaccination Child Preschool Female Reagent Kits Diagnostic Peptides business medicine.drug |
| Zdroj: | Clinical and Vaccine Immunology. 15:168-171 |
| ISSN: | 1556-679X 1556-6811 |
| DOI: | 10.1128/cvi.00364-07 |
| Popis: | We evaluated the T-SPOT.TB and Quantiferon-TB Gold In tube (QFN-G-IT) tests for diagnosing Mycobacterium tuberculosis infection. T-SPOT.TB was more sensitive than QFN-G-IT in diagnosing both active and latent infection. Both gamma interferon tests were unaffected by prior Mycobacterium bovis BCG vaccination. Among children who were not BCG vaccinated but had a positive tuberculin skin test, QFN-G-IT was negative in 53.3% of cases, and T-SPOT.TB was negative in 50% of cases. |
| Databáze: | OpenAIRE |
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