| Autor: |
Herbert Malkus, H. Mckennis, W. Eisenhart, A. Castro, Edward R. Bowman, Nobuo Monji |
| Rok vydání: |
1979 |
| Předmět: |
|
| Zdroj: |
Clinica Chimica Acta. 95:473-481 |
| ISSN: |
0009-8981 |
| DOI: |
10.1016/0009-8981(79)90198-0 |
| Popis: |
We have developed an automated nonequilibrium procedure for the radioimmunoassay of nicotine. The use of a unique iodinated nicotine derivative in this procedure gave a sensitivity of 10 micrograms/l for nicotine with a between-run precision of 7.4% and within-run precision of 6.0%. Nicotine levels of 60 to 67 micrograms/ml were found in subjects 15 min after smoking one standard cigarette. The technique herein reported is a very rapid, and sensitive radioimmunoassay for nicotine and facilitates the determination of nicotine in smoking subjects during the actual process of smoking. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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