Evidence against Human Bone Marrow Lymphocytes being Committed Haemopoietic Stem Cells
| Autor: | Michele Baccarani, Sven-Aage Killmann |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Time Factors
Bone Marrow Cells Biology Tritium Pernicious anaemia Bone Marrow hemic and lymphatic diseases Precursor cell Anemia Pernicious medicine Humans Erythropoiesis Lymphocytes Edetic Acid Stem cell transplantation for articular cartilage repair DNA Hematology Hematopoietic Stem Cells Blood Cell Count Culture Media Endothelial stem cell medicine.anatomical_structure Immunology Autoradiography Bone marrow Stem cell Thymidine Adult stem cell |
| Zdroj: | Scandinavian Journal of Haematology. 9:339-342 |
| ISSN: | 0036-553X |
| DOI: | 10.1111/j.1600-0609.1972.tb00950.x |
| Popis: | In 11 patients with untreated pernicious anaemia the percentage and the 3H-thymidine labelling index of bone marrow lymphocytes and of E1 erythroblasts were determined. It is concluded that bone marrow lymphocytes cannot account for the expected flux into erythropoiesis; hence they cannot be the immediate progenitor's (committed stem cells) of erythroid precursors. It is suggested that in man the rapidly turning over committed stem cells may have the morphology of already recognized precursor cells. |
| Databáze: | OpenAIRE |
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