Comparison of response to cardiac resynchronization therapy in patients with sinus rhythm versus chronic atrial fibrillation
| Autor: | Martin J. Schalij, L. Van Erven, Eric Boersma, Jeroen J. Bax, Paul Steendijk, Gabe B. Bleeker, Sander G. Molhoek, Ernst E. van der Wall |
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| Přispěvatelé: | Cardiology |
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty New York Heart Association Class medicine.medical_treatment Bundle-Branch Block Cardiac resynchronization therapy Internal medicine Atrial Fibrillation medicine Humans Sinus rhythm cardiovascular diseases Aged Heart Failure Exercise Tolerance Ejection fraction Bundle branch block Left bundle branch block business.industry Cardiac Pacing Artificial Stroke Volume Atrial fibrillation medicine.disease Heart failure Chronic Disease cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | American Journal of Cardiology, 94, 1506-1509. Elsevier Inc. |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2004.08.028 |
| Popis: | Cardiac resynchronization therapy (CRT) is a new therapeutic option for patients who have drug-refractory end-stage heart failure. Much information has been obtained from patients who have sinus rhythm, but the use of CRT in patients who have chronic atrial fibrillation (AF) has not been studied extensively. Accordingly, we evaluated the clinical response and long-term survival rate of CRT in patients who had heart failure and chronic AF, and the results were compared with those in patients who had sinus rhythm and who underwent CRT. Sixty patients who had end-stage heart failure (30 had sinus rhythm and 30 had chronic AF), New York Heart Association classes III to IV, left ventricular ejection fraction35%, QRS interval120 ms, and a left bundle branch block received a biventricular pacemaker. New York Heart Association class, Minnesota Quality of Life score, and 6-minute walking distance were evaluated at baseline and after 6 months of CRT. Long-term follow-up was/=2 years. New York Heart Association class, Minnesota Quality of Life score, and 6-minute walking distance improved significantly in the 2 groups after 6 months of CRT. The number of nonresponders was greater among patients who had AF. Nevertheless, the long-term survival rate was comparable between patients who had sinus rhythm and those who had AF. Patients who had AF demonstrated comparable benefit from CRT as those who had sinus rhythm. |
| Databáze: | OpenAIRE |
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