Potential role of the apelin-APJ pathway in sex-related differential cardiotoxicity induced by doxorubicin in mice
| Autor: | Varsha G. Desai, Ana Azevedo‐Pouly, Vikrant Vijay, Bounleut Phanavanh, Carrie L. Moland, Tao Han, Javier Revollo, Baikuntha Aryal, V. Ashutosh Rao, James C. Fuscoe |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of applied toxicology : JATREFERENCES. |
| ISSN: | 1099-1263 |
| Popis: | Preclinical and clinical findings suggest sexual dimorphism in cardiotoxicity induced by a chemotherapeutic drug, doxorubicin (DOX). However, molecular alterations leading to sex-related differential vulnerability of heart to DOX toxicity are not fully explored. In the present study, RNA sequencing in hearts of B6C3F |
| Databáze: | OpenAIRE |
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