Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model

Autor:	T. Ye. Kurilskaya, B. K. Baduyev, I. V. Babushkina, Yu. I. Pivovarov, A. S. Sergeyeva, G. B. Borovsky
Rok vydání:	2011
Předmět:	dislipoproteinemia Transplantation - action Chemistry Biophysics Medicine Molecular Medicine Fraction (chemistry) transplantation of cells and nucleus
Zdroj:	Bûlleten' Sibirskoj Mediciny, Vol 10, Iss 6, Pp 23-29 (2011)
ISSN:	1819-3684 1682-0363
DOI:	10.20538/1682-0363-2011-6-23-29
Popis:	Research objective was to compare effects of transplantation of cells and their nucleus on model alimentary dislipoproteinemia. Experiment is executed on the rabbits containing on an atherogenous diet. In blood serum of animals studied changes of a lipide exchange, in a liver — level of stresses-proteins, morphological changes and the maintenance of markers of an apoptosis and a proliferation. Also estimated the area of atherogenous plaques and a thickness of intima of an aorta. It is shown that unlike cellular transplantation, introduction of nucleus led to more expressed therapeutic effect and inhibition of expansion of leading links of an atherogenesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0aecff8d15c4bb98bb419d9100bf5d https://doi.org/10.20538/1682-0363-2011-6-23-29 Zobrazit plný text záznamu