Saccular and Cochlear Endolymphatic Potentials in Experimentally Induced Endolymphatic Hydrops of Guinea Pigs
| Autor: | Eiichi Arakawa, Masaaki Rokugo, Kenji Ohyama, Toshimitsu Kobayashi, Naoki Inamura, Jun Kusakari |
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| Rok vydání: | 1986 |
| Předmět: |
Time Factors
Guinea Pigs Labyrinth Diseases Perilymph Membrane Potentials Asphyxia Endolymph Furosemide otorhinolaryngologic diseases medicine Animals Edema Saccule and Utricle Endolymphatic hydrops Meniere Disease Cochlea business.industry Labyrinthine Fluids General Medicine Anatomy medicine.disease medicine.anatomical_structure Otorhinolaryngology Saccule business |
| Zdroj: | Acta Oto-Laryngologica. 101:27-33 |
| ISSN: | 1651-2251 0001-6489 |
| Popis: | Saccular and cochlear endolymphatic potentials (SEP and CEP) were recorded in 33 normal animals. We confirmed that SEP is not produced in the saccule per se, but is a potential leak from the cochlea. CEP was reduced to one-tenth of the original value when it reached the saccule. Endolymphatic hydrops was provoked in 32 animals, and CEP and SEP were successfully recorded in 29 and 20 cases, respectively. The measurements were performed in the 2nd, 4th and 12th postoperative week. Both CEP and SEP decreased in magnitude as time elapsed after the surgery. This reduction is attributed to the strial dysfunction. In advanced hydrops, CEP transmission to the saccule is greatly inhibited. It is concluded that the saccular dysfunction can occur in the hydropic ear. |
| Databáze: | OpenAIRE |
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