The ophthalmological findings in autosomal recessive severe juvenile arteriosclerosis
| Autor: | Ilkka Kaitila, Christina Raitta |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Eye Diseases Arteriosclerosis Systolic hypertension Visual Acuity Genes Recessive 030204 cardiovascular system & hematology Fundus (eye) Amblyopia Constriction 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine.artery Diseases in Twins Humans Medicine Fluorescein Angiography Child Intraocular Pressure Aorta Esotropia medicine.diagnostic_test business.industry Retinal Vessels General Medicine Anatomy Retinal vascular tortuosity medicine.disease Fluorescein angiography 3. Good health Ophthalmology Hyperopia Cardiology Female business Calcification |
| Zdroj: | Acta Ophthalmologica. 63:175-182 |
| ISSN: | 1755-375X |
| Popis: | Severe juvenile arteriosclerosis (JAS) is a rare, fatal disease with probably autosomal recessive inheritance. Precocious arterial murmurs and calcification of aorta and major arteries are associated with anaemia, growth retardation, prolonged systolic hypertension, gradual renal failure, gastrointestinal perforations, and early death. The ophthalmological findings in 5 boys and 1 girl between 7 and 17 years of age were retinal vascular tortuosity of main vessels, pre-capillary arterioles and post-capillary venules, sausage-like bulging of central main arterioles and microaneurysms of arterioles of the central fundus. Narrowing and local constriction was a typical feature of peripheral arterioles. The combination of findings documented by fluorescein angiography in 4 children was typical for severe juvenile arteriosclerosis. |
| Databáze: | OpenAIRE |
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