| Popis: |
Starch based Carbon nanotubes-iron oxide (CNT-IO) and Carbon Nanotubes-Zirconium oxide (CNT-ZO) Nanocomposites (NCs) were fabricated by using facile microwave irradiation technique from different plant-based starch sources namely Tapioca sago (TS), Hordeum vulgare (HV) and Eleusina coracona (EC) and metal oxide precursor solutions. These NCs were studied using different characterization techniques such as SEM, TEM, XRD, Raman spectroscopy and FTIR spectroscopy. The Structural morphology of Starch based CNT-IO and CNT-ZO NCs observed like a rolled tubular structures and exhibiting strong blue luminescence with the charge transfer between CNT and Metal oxide. We have evaluated the anti-proliferative and anti-oxidant activity of starch-based CNT-IO and CNT-ZO NCs using MCF-7 cell line compared with the standard drug camptothecin and DPPH assay. Among the various NCs studied antiproliferative activity, CNT-IO and CNT-ZO obtained from starch source Eleusina coracona was effective with IC 50 values of 12.3 and 18.2 µg/mL respectively. Moreover, the enhanced radical scavenging activity has also been observed for these NCs. |
