Comparison of the Effects of Sufentanil and Fentanyl on Postoperative Sleep Quality of Children Undergoing Tonsillectomy and Adenotomy: A Randomized Controlled Trial
| Autor: | Bijia Song, Jingjie Wan, Yang Li, Zhen Li, Junchao Zhu, Man Luo, Wenxin Wei |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Sedation
medicine.medical_treatment fentanyl law.invention Fentanyl Sufentanil 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine sufentanil Randomized controlled trial children law Nature and Science of Sleep medicine pain Athens insomnia scale Applied Psychology Original Research business.industry postoperative sleep quality Perioperative Tonsillectomy 030228 respiratory system Anesthesia medicine.symptom business 030217 neurology & neurosurgery Postoperative nausea and vomiting medicine.drug |
| Zdroj: | Nature and Science of Sleep |
| ISSN: | 1179-1608 |
| Popis: | Yang Li,1,* Bijia Song,2,* Zhen Li,3 Jingjie Wan,4 Man Luo,1 Wenxin Wei,1 Junchao Zhu1 1Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China; 2Department of Anesthesiology, Friendship Hospital of Capital Medical University, Beijing, People’s Republic of China; 3Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine, Shanghai, People’s Republic of China; 4Department of Anesthesiology, First Affiliated Hospital of Suzhou University, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junchao ZhuDepartment of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of ChinaTel +86 18940257257Email zhujunchao1@hotmail.comObjective: The primary purpose was to compare the effects of sufentanil and fentanyl on the postoperative sleep quality. And the secondary purposes were to evaluate perioperative hemodynamics, postoperative pain and complications of children undergoing tonsillectomy and adenotomy.Methods: Seventy-six patients were randomly assigned to the sufentanil or fentanyl group. The subjective sleep quality was assessed by the Athens Insomnia Scale (AIS) on the night before surgery (Sleep preop 1), the first night after surgery (Sleep POD 1), and the third night after surgery (Sleep POD 3). The Faces Pain Scale-Revised (FPS-R) was used to evaluate the postoperative pain level 24 hours after surgery. The Observer’s Assessment of Alertness and Sedation (OAA/S) scale was used to assess the level of sedation in children. Perioperative hemodynamics and adverse effects were also evaluated.Results: The AIS score in the sufentanil group was significantly lower at Sleep POD 1 and Sleep POD 3 (P < 0.001, respectively). Children in the sufentanil group had significantly lower FPS-R scores at 2, 4, and 6 hours after surgery (P = 0.004, P = 0.004, and P = 0.001, respectively). The intraoperative hemodynamic parameters were more stable (P < 0.05, respectively) and the OAA/S scores at 2 hours after surgery were lower in the sufentanil group (P < 0.05). There was no significant difference in the incidence of postoperative nausea and vomiting between the two groups (P = 0.435).Conclusion: Children undergoing tonsillectomy and adenotomy after general anesthesia who received sufentanil had better postoperative sleep quality and less postoperative pain at 2, 4, and 6 hours post operation. Moreover, children who received sufentanil showed better hemodynamic stability during surgery. Therefore, sufentanil should be considered as a better choice to facilitate rapid recovery in children following tonsillectomy and adenotomy.Keywords: postoperative sleep quality, pain, sufentanil, fentanyl, children |
| Databáze: | OpenAIRE |
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