Introduction of new clones of penicillin-nonsusceptible Streptococcus pneumoniae in Hong Kong
| Autor: | Lily Tsang, Raymond W. H. Yung, D. J. Lyon, Augustine F. B. Cheng, Margaret Ip |
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| Rok vydání: | 2002 |
| Předmět: |
Microbiology (medical)
Serotype medicine.drug_class Epidemiology Penicillin Resistance Antibiotics Microbial Sensitivity Tests Biology medicine.disease_cause Pneumococcal Infections Microbiology Drug Resistance Multiple Bacterial Streptococcus pneumoniae medicine Humans Serotyping Antibacterial agent Streptococcaceae biology.organism_classification medicine.disease Virology Anti-Bacterial Agents Bacterial Typing Techniques Electrophoresis Gel Pulsed-Field Penicillin Pneumococcal infections Chloramphenicol Multilocus sequence typing Hong Kong medicine.drug |
| Zdroj: | Journal of clinical microbiology. 40(4) |
| ISSN: | 0095-1137 |
| Popis: | Analysis of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) isolates in Hong Kong by use of a combination of antibiogram typing, serotyping, multilocus sequence typing, and pulsed-field gel electrophoresis indicated that the dissemination of PNSP was the result of the spread of international clones: variants of the Spain 23F -1 or Spain 6B -2 clones were the predominant PNSP isolates from 1994 to 1997 and remained so, but Taiwan 19F -14 and Taiwan serotype 6B clones were disseminated in Hong Kong in 1999 and 2000. Concomitant changes in antibiotic susceptibility profiles, with the rate of susceptibility to chloramphenicol rising from 10% in the period from 1994 to 1997 to 31% ( P < 0.001) in 1999 and 2000, were noted to accompany the shift of clones. |
| Databáze: | OpenAIRE |
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